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CAIBI ASSESSMENT

Open Syringe Pump v4

CAIBI VERDICTWORTH CONSIDERING

A modular open laboratory syringe-pump platform with a compact mechanical pump, a separate controller and serial control for repeatable research fluid handling.

Build or buy?

Compare the documented build with the purchase reference.

Build it yourself

Known parts cost£203Build total not establishedOne pump and controller; power and fluid-path consumables extra
Time
The source states less than 10 minutes for pump assembly once the fabricated and sourced parts are ready; procurement, fabrication, electronics, setup and calibration are additional.
Difficulty
4/5
Physical processes
FDM printer or print service · Metal fabrication access for the bent aluminium frame · Electronics assembly tools · Hex and hand tools
See build requirements →

Purchase reference

Buy price referencePrice not checkedNo priced alternative recorded

Check the source for the exact model, availability and what is included.

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Purchase comparison not yet priced
What the prices cover

The current v4 documentation estimates about $175 per pump plus $100 per controller. CAIBI combines those source figures for a one-pump first setup and uses the dated 4 Sep 2026 FX research snapshot for the approximate GBP display. One controller can serve up to four pumps, so multi-pump economics differ.

Includes: Source-estimated one v4 pump hardware route; Source-estimated one controller hardware route.

Not included: Shipping and taxes; Bent aluminium and FDM fabrication service or owned fabrication equipment; Electronics assembly labour or outsourced controller assembly; 12 V power supply if not already owned; Syringe, tubing and experiment-specific fluid-path consumables; Calibration equipment and operator time.

Build evidence recorded 5 Sep 2026. Currency conversions are approximate.

Commercial laboratory pumps vary materially in channel count, calibration, accuracy claims, fluid-path compatibility, support and validation. The open v4 source also shares one controller across up to four pumps. CAIBI therefore records the source build economics without converting an unlike commercial pump price into a savings claim.

GLOBAL purchase/source reference ↗GLOBAL purchase/source reference ↗
BUILD AT A GLANCE

Source view and main parts

Check the source ↗
Syringe pump v4 assembly photographSyringe pump v4 assembly photograph · Karpova Lab / HHMI Janelia ↗
PHYSICAL BUILD9 key parts or groups
No.Source specification
01Bent aluminium pump frame and current v4 fasteners
02FDM printed syringe clamps
03Stepper motor
04Integrated pull and push limit switches
05Controller PCB with TMC5041 motor drive and user-interface electronics
06Display
07Connector module for the selected power and communication route
0812 V supply for the source-safe baseline configuration
09Syringe plus experiment-specific tubing
Full source specifications
  1. Bent aluminium pump frame and current v4 fasteners
  2. FDM printed syringe clamps, carriage and related mechanical parts
  3. Stepper motor, 2 mm pitch leadscrew, linear shaft and bearings
  4. Integrated pull and push limit switches
  5. Controller PCB with TMC5041 motor drive and user-interface electronics
  6. Display, buttons and rotary encoder
  7. Connector module for the selected power and communication route
  8. 12 V supply for the source-safe baseline configuration
  9. Syringe plus experiment-specific tubing, outlet and fluid-path consumables
TOOLS / PROCESSES4 involved
  • FDM printer or print service
  • Metal fabrication access for the bent aluminium frame
  • Electronics assembly tools
  • Hex and hand tools
The real-world workYOU STILL HAVE TOThe real-world work
  • Source or fabricate the exact v4 bent aluminium and printed mechanical parts
  • Assemble the rods, bearings, leadscrew, carriage, clamps, stepper and limit switches
  • Build or source the controller electronics and inspect every connection before power is applied
  • Use the source-safe 12 V route unless the experiment genuinely requires and validates a different supported setup
  • Fit the real syringe and fluid path and check clearances, loading and limit-switch operation
  • Calibrate delivered volume and flow with the actual syringe, tubing and fluid
  • Manage experiment-specific physical, fluid and contamination risks
  • Validate suitability for the intended research process rather than assuming an open design is a certified instrument
THE BUILD SEQUENCE

How it comes together

1Preparation

  1. Lock the v4 route before ordering

    Use the current v4 branch and documentation rather than mixing older v2 or v3 mechanical parts into the build. The design changed materially in August 2025 and now uses 49 parts, a bent aluminium frame and FDM printed components.

    AI + YOU
  2. Fabricate the pump mechanics

    Prepare the source-specified aluminium frame and printed parts, then inspect hole positions, bearing fits and leadscrew alignment before assembly. The published short assembly time starts after this fabrication and sourcing work is complete.

    YOU
  3. Assemble the pump and limits

    Install the stepper, leadscrew, guide shaft, carriage, syringe clamps and pull/push limit switches. Confirm free travel by hand and make sure a limit switch will act before the carriage can force the syringe beyond its intended travel.

    YOU

2Build and assembly

  1. Build and inspect the controller

    Assemble or source the current controller and connector module, then inspect orientation, connectors and wiring before power. A single controller can run up to four pumps, so label channels and cables before expanding the system.

    YOU
  2. Load software and prove motion

    Install the current software route, configure the selected connector and verify manual and serial control with an unloaded or safe test setup before using an experimental fluid path.

    AI + YOU
  3. Configure the actual syringe

    Enter the real syringe diameter and requested flow or volume values. Use the source equations for planning, but keep theoretical resolution separate from delivered-volume accuracy.

    AI + YOU

3Configure and test

  1. Calibrate the complete fluid path

    Measure what is actually delivered through the selected syringe, tubing and outlet using the real fluid. The source explicitly notes that tubing elasticity, fluid properties and plunger friction can dominate the theoretical microstep resolution.

    YOU
  2. Validate the research workflow

    Run repeatability checks at the volumes and flow rates that matter to the experiment, record the result and re-check after changes to syringe size, tubing, fluid, voltage or mechanical setup.

    AI + YOU

Benchmark this project

Use the Open Syringe Pump v4 prompt. Compare what different models deliver, then add what happened when you tried it.

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CAIBI adaptation · Prompt 1.0 · Project source

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Benchmark results 0

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AI IN THIS PROJECT

Get AI help on this build

CAIBI · AI CAN HELP

AI can help with

  • Navigate the v4 BOM, mechanical source, controller files and documentation
  • Help distinguish current v4 parts from older v2 and v3 hardware
  • Explain controller configuration and serial commands
  • Calculate source-defined flow relationships from syringe diameter and plunger speed
  • Help build calibration plans and data-logging scripts for the actual fluid path
  • Review firmware or host-side integration changes before physical testing
  • Help troubleshoot repeatability using measured results rather than theoretical microstep claims
CAIBI · AI CAN'T DO

You still need to

  • Source or fabricate the exact v4 bent aluminium and printed mechanical parts
  • Assemble the rods, bearings, leadscrew, carriage, clamps, stepper and limit switches
  • Build or source the controller electronics and inspect every connection before power is applied
  • Use the source-safe 12 V route unless the experiment genuinely requires and validates a different supported setup
  • Fit the real syringe and fluid path and check clearances, loading and limit-switch operation
  • Calibrate delivered volume and flow with the actual syringe, tubing and fluid
  • Manage experiment-specific physical, fluid and contamination risks
  • Validate suitability for the intended research process rather than assuming an open design is a certified instrument
Original source AI use and prompts
SOURCEThe original project does not publish an AI prompt

The prompts below are CAIBI helpers for this build. They are not presented as instructions from the creator.

CAIBI STARTING PROMPTS

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Each prompt tells AI to keep the original project source as the reference and to flag anything you must verify on the real build.

Ways to take it further
AFTER THE FIRST BUILD

Ways to take it further

One pump plus one controllerUp to four pumps on one controllerManual controller operationRemote serial-control integrationDIN-rail vertical mounting
More routes and resources
OTHER WAYS TO GET THERE

You do not have to follow one route.

REVIEWED RESOURCES

Useful places beyond the main source

SOURCE · CAIBI · BUILDERS

What supports the verdict

SOURCEKarpova Lab

Open Syringe Pump v4 is the current Karpova Lab route. The repository default branch is v4, the design was released in August 2025, and the current documentation publishes the v4 cost, assembly and performance model. A 2026 Karpova-led research preprint cites the project for live experimental use, which supports current-use context but is not independent builder validation.

Open source ↗
CAIBIWORTH CONSIDERING

This is a credible open instrument rather than a classroom mock-up. The current v4 route publishes the hardware, software and build documentation, and its controller can run up to four pumps. It is most compelling for research teams that value repairability, custom control and integration with their own experiments. A commercial pump is still the lower-risk choice when procurement support, validated performance or regulated use matters more than openness.

Evidence: Strong

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What we want to know

What happened when you actually tried to make it.

  • Did it work?
  • Actual time and cost
  • What did you change?
  • What was harder than the source suggested?
  • Would you build it again?